Baldness

BaldnessMale pattern baldness, professionally known as androgenic alopecia, is a common phenomenon that affects both men and women, but in general, the higher incidence is observed in men. Androgenic alopecia is present in about 35 million men in the United States. The first signs of baldness with men can appear as early as teenage years and then progress through the years; women have symptoms more frequently around menopause. The hair, both in men and women, starts first to thin, then gets shorter and loses pigment. Then it thins more and more till complete baldness. The main cause of male pattern baldness lies in male sex hormones, but also heredity has its part. The rate and extent of hair loss depends also on the individual's genetic makeup, thus the genetic analysis can predict your chance of developing baldness.

Androgenic alopecia, generally affects 40 percent of all men and women

Baldness development is influenced by many environmental and genetic factors, where the influence of heritability is confirmed to be as much as 80 percent. Scientists assume that many genes are involved in the development of baldness but so far only few have been revealed. One of the most important genes is androgen receptor (AR), which has been shown to play a key role in the development of androgenic alopecia. The fact that hair loss is related to hormones called androgens (such as testosterone hormones), contributed a lot to its discovery. Androgenic hormones are important for the development of primary sexual characteristics before the birth and development of secondary sexual characteristics later, during puberty. On the other hand, androgen receptors have binding sites for androgen hormones and so provide an adequate response to the presence of the hormones in the body. Hormone-receptor complexes then bind to DNA and regulate the activity of specific genes, including genes that are important for hair growth. Research shows that the mutation in the AR gene provides increased activity of these receptors in the hair follicles, making us less susceptible to hair loss.