Some people perceive pain more strongly than others. This is connected to the COMT gene, whose role is to regulate the level of catecholamines and enkephalins. Their levels are connected to the level of pain that a person senses. Increased activity of this gene is linked to lower pain sensitivity. A connection between the rs6269 marker and pain sensitivity has been established. Persons with type A in this place are more sensitive to pain than persons with type G.
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