More details about fat intake and body mass index

The APOA5 gene encodes an apolipoprotein. It is a protein that plays an important role in defining the plasma triglyceride level which is one of the main risk factors for the development of coronary artery disease. They are the building blocks of various larger lipoprotein particles such as the CLDL, HDL, etc. Polymorphisms in the APOA5 gene can influence the concentration of plasma triglycerides and consequently effect bodily changes such as the change in body weight.

Thirteen percent of Europeans supposedly carry the G allele and thus have a reduced chance of becoming overweight. However, this effect was not displayed if less than 30% of the energy was obtained from the consumed fats. This occurrence was observed in men and women alike.

It must be noted that also people with a G allele can gain a lot of weight. Unlike people without the G allele, they do not need to vigilantly count calories of consumed fats, but in the long run and in cases of excessive intake of calories, they may also gain weight.

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