Genetic testing for peripheral arterial disease
Peripheral arterial disease restricts blood circulation or even causes a complete block in the arteries of the lower extremities. It is caused by deposits of fat, calcium and inflammation cells in the vessel walls. The result is a narrowing of the vessel lumen and worse perfusion of the extremity, causing typical symptoms of disease. The most common are pain in the legs while walking, muscle weakness, as well as patchy pale skin of the legs. It is a common occurrence, a mild form of it affecting one fifth of the population after the age of 55 in developed countries.
Why should you have your DNA analysed for predisposition to peripheral arterial disease?
The disease has an important genetic origin for it is more commonly observed in the patient's relatives than in the rest of the population. It is especially common in people who have an increased genetic susceptibility to nicotine addiction.
How is peripheral arterial disease prevented or treated?
Medications ease the pain and prevent disease progression by lowering the level of fats and by regulating the high blood sugar and blood pressure. However, adequate physical activity and smoking cessation are essential therapy supplements. Preventive measures, taken seriously by most people only if they are aware of their susceptibility to the disease, are of utmost importance in this disease.
More information about genetic testing for diseases.