Genetic testing for atherosclerotic coronary artery disease
Atherosclerotic coronary artery disease is a condition where the accumulation of cholesterol, calcium and inflammatory cells in a vessel wall narrows the lumen of the vessels which supply nourishment to the heart. The development of atherosclerosis is not completely clear, but it is generally thought to involve a state of chronic inflammation in the arterial walls, where the presence of the "bad cholesterol" plays an important role. It is carried by a special carrier for fats in the blood (LDL). Atherosclerotic coronary artery disease is the leading cause of death in the developed world, killing 30% of people. It is advisable to have your genome checked in order to be able to institute prophylactic actions.
Why should you have your DNA analysed for predisposition to atherosclerotic coronary artery disease?
By checking your genome, we search for gene variants which play an important role in the synthesis of the "bad cholesterol", which can significantly influence the development of this dangerous disease and a heart attack. An early care for physical activity and a healthy, non-fatty food can successfully halt the development of this disease. Thus, information about an increased risk can be very useful. Once the vessels are blocked, these measures are no longer effective.
How is atherosclerotic coronary artery disease prevented or treated?
The first line of treatment are drugs which reduce the load on the heart; later on, balloon dilatation, stent placements or a bypass surgery have to be considered.
More information about genetic testing for diseases.