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Type 2 Diabetes
Type 2 diabetes mellitus is also known as the non-insulin-dependent diabetes mellitus (NIDDM). It is a chronic disease affecting the metabolism of glucose which is the main fuel of the human body and the principal source of energy for all body cells. Glucose is obtained from the ingested food as well as from the body stores - the liver and muscles. During food digestion, glucose is absorbed from the intestine into the blood circulation from where it enters the cells with the help of insulin. Insulin is a hormone produced by the pancreas. When we eat, insulin is secreted into the blood where it circulates and enables glucose to enter the cells, thereby lowering the blood glucose level. The decrease in blood glucose concentration in turn results in a diminished insulin secretion from the pancreas.
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Your genetic analysis indicated that you have a decreased risk for the development of type 2 diabetes mellitus (T2 DM). Prevalence of this disease in the European population is 2-3 %. Despite a relatively low chance of getting this disease, the risk still exists. You can do a lot yourself to prevent its appearance. It is especially important to adopt a healthy lifestyle that drastically lowers the chance of the appearance of this disease. Even in the presence of a family history of T2 DM, one may prevent its appearance or at least postpone or reduce the chance of its appearance by adhering to a dietary plan and engaging in physical activity. These measures also reduce the incidence and severity of the serious consequences of this disease, should it have been diagnosed in your case.
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GenePlanet Medical Team
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The influence of genes
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Type 2 Diabetes belongs to the class of diseases whose appearance is attributable to the genes to a large extent. Heritability of such diseases is relatively high, but it usually does not surpass 50%. Genes often determine congenital malformations that are unresponsive to environmental influences; however, an adequate behaviour and lifestyle can nevertheless substantially influence the appearance of the disease.